People often mistake physical and chemical drug dependence for addiction; however, a person can become dependent on a substance without being addicted to it. When drugs that alter the mind are introduced into the body, changes occur in the brain and its chemical makeup. Certain chemical messengers are affected. These chemical messengers, or neurotransmitters, are what tell a person how to feel, which can therefore impact behaviors. For example, most drugs act on the pleasure and reward centers in the brain. Levels of neurotransmitters like dopamine and serotonin are increased, which is what produces the desired “high.” Inhibitions are often lowered; sociability is increased; and decision-making abilities are impaired. Those using mind-altering drugs are then likely to put themselves into potentially dangerous situations and therefore be at risk for accidents, injuries, or other actions that may have adverse consequences (like potentially dangerous sexual interactions, for instance).
Some drugs, such as stimulants like cocaine, methamphetamine, and prescription ADHD medications (Adderall and Ritalin), speed up central nervous system functions. Heart rate, body temperature, respiration rate, and blood pressure are all increased, along with energy levels, focus and attention, and excitement. The high from stimulant drugs can be very intense and may decrease a person’s appetite and keep them awake for long periods of time.
Other drugs like opioids, which include heroin and prescription painkillers (e.g., fentanyl, OxyContin, Vicodin, Percocet, morphine, etc.), benzodiazepine sedatives and tranquilizers (e.g., Valium, Xanax, Ativan, Klonopin, etc.), and marijuana slow down functions of the central nervous system, leaving a person feeling relaxed, drowsy, sluggish, and sedated. These drugs reduce stress and anxiety temporarily. Levels of the neurotransmitter GABA (gamma-aminobutyric acid), which acts as a natural tranquilizer, are increased by their presence.
When an illicit drug like one of these is taken regularly and often, the brain may begin to try and account for the changes to its chemical makeup. The brain attempts to keep itself balanced, and in so doing, it can then stop transmitting, reabsorbing, and even producing some of the natural neurotransmitters it needs to function. Regions of the brain related to impulse control, mood regulation, feelings of pleasure, memory, learning functions, and stress management are then negatively impacted.
Tolerance is usually the first thing that happens with chronic drug use. The brain will no longer be affected by regular amounts of the drug, and higher doses may be needed to feel the drug’s effects. As dosage is increased, the brain struggles to keep up and rebalance itself, which can lead to drug dependence. Drug dependence is a physical and chemical manifestation of chronic drug use. When someone is dependent on a drug, they will often suffer from cravings and difficult withdrawal symptoms when the drug wears off. Drug withdrawal symptoms are often the opposite of a drug’s effects, and they occur when levels of the brain’s neurotransmitters are disrupted by regular drug abuse. Drug dependence generally is present in someone battling addiction; however, a diagnosis of addiction requires more than just this physical aspect.
Signs of Addiction
Addiction is a brain disease, but its primary indicator is a loss of control over the ability to make choices related to stopping or continuing certain actions that then leads to negative behavioral consequences, the journal Evaluation and the Health Professions states. Addiction, therefore, must have a behavioral component to it.
The Diagnostic and Statistical Manuel of Mental Disorders (DSM) is the standard diagnostic tool published by the American Psychiatric Association (APA) and widely used by medical and mental health professionals. The most current DSM, the DSM-5, has 11 criteria for diagnosing drug addiction.
As published by NIDA, at least two of the following must be present in the span of a year:
- Inability to stop using drugs despite a strong desire, or even many attempts, to do so
- Taking more drugs at a time, or more taking them more often, than originally intended
- Drug cravings
- A great deal of time spent working on ways to obtain drugs, using them, and recovering from drug use
- Social and recreational activities that were previously a priority are no longer valued and participation in them is often replaced by activities related to drug abuse instead
- Repeatedly using drugs in situations that are deemed hazardous or physically dangerous
- Despite the negative impact on relationships and the adverse social ramifications, continued drug use
- Continued use of drugs in spite of the knowledge that using them is creating emotional, social, and physical consequences
- Failure to consistently attend to important work, school, and family obligations as a result of drug abuse
- Drug tolerance indicated by regular use of the drug having less effect and the need to take more to feel intoxicated
- Drug withdrawal symptoms when drug wears off, which may include gastrointestinal upset, headaches, depression, anxiety, insomnia, irregular heart rate and blood pressure, irritability, agitation, and fatigue
With drug addiction, a person will often need to keep taking drugs in order to feel “normal” and balanced due to the chemical changes in the brain. Drugs can take a toll on a person’s body as a result. Appetite changes, weight fluctuations, health problems, and malnutrition are often signs of a drug problem. A person may also become less concerned with personal hygiene. Physical appearance may no longer be important.
Mood swings, aggression, hostility, and violence, as well as feelings of agitation and irritability are common side effects of addiction. Erratic and unpredictable behaviors, depressed moods, and difficulty feeling pleasure are often the result of changing brain chemistry related to chronic drug use. Social withdrawal, increased secrecy, and relationship issues are additional ramifications of addiction and problematic drug use. Shame, guilt, anger, and denial are common emotions that go hand in hand with drug addiction.
A specialized addiction treatment program can help to manage drug cravings and withdrawal symptoms, thus curbing the “need” to keep taking drugs. These programs can also provide therapeutic and supportive care to help clients and families work through the behavioral, social, emotional and interpersonal relationship issues that generally accompany addiction and drug abuse.
If you believe you are a drug addict, rest assured that addiction is treatable. Reach out for help today.
Credited to: Oxford Treatment